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6胜肽.丁+蛋+大豆+酪+絲+魚

6胜肽.丁+蛋+大豆+酪+絲+魚.食品級

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Synthesizing of protein:

The factory of the manufacturing protein checks the sugar body(ribosome), can let the message come over also to synthesizes the protein here.It has two important positions:The P site and A site.The representative of the P has another the polypeptide, the A represents the sour amino acid of the amino.

Synthetic way is:

The AUG on the mRNA to should of the CAU(according to usual practice, the RNA reads the method certainly by 5'to 3') will bring a methionine with sour amino, if next is a CCG, opposite should of the CGG will take the sour proline of the amino, these two amino are sour and then will combine the row, the amino of the P site is sour and then will come over, with the sour formation peptide of the amino of the A site (the peptide bond) and become a pair of peptide (dipeptide), will move 3 pits downwards again after sweet sour, then is changed into three peptide(tripeptide) by a peptide (dipeptide), depend on this kind to push.This process is the peptide of the P siteu Move the amino of the A site sour, and move with 3,three alkali,the end is to read the in-frame(same"read the frame" are called the in-frame) to terminate the password son(UAA/UAG/UGA), the protein synthesizes and then will terminate, the lately- synthesized protein will be dropped down, the big and small unit(subunit) that checks the sugar body also will be separated.The big and small unit that usually checks the sugar body is at the time of synthesizing the protein and then would link together, separating for the meeting while synthesizing to terminate. The amino sour is an unit of minimum human body, two strings with sour amino are called a pair of together, Three strings with sour amino are called three peptide together, The sour above string of four amino is many peptide together, 50 strings with sour amino are so-called proteins together.

The peptide Is a shorter protein, many peptide,Have the important living creature function or activity:

The peptid key(the peptide bond) by a peroxide with sour and sour amino, with an one sour amino of the amino , the C-N key that goes to dehydrate the match to respond and become, have a pair of property of keys, are on same flat surface with close together ltogether six atomses, So the C-N key can't turn to move freely;The peptid key is the basic unit that constitutes the protein structure, count for much, please watch for to study its stereoscopic composing.

In addition to water, in the bio-chemical the first important living creature numerator that runs into is the amino sour.Explain the sour structure and property of the amino , see its long appearance, do what use.In fact, all bio-chemical numerators, can be divided into the structure and the property both side to explain.

The amino is sour although have 20 kinds of, its basic structure framework is alike;We will describe the sour structure of familiar amino inside the body of these living creatures, the classification explains the pole of its side chain regiment or not very sex characteristic;Design a subway map for imitating, use to the structure relation of explaining various with sour amino , and the convenience remembers;But notice this diagram to metabolize the path not.Then see how two with sour amino link the peptide.

A lot of such peptide.HAVE already had the physiology function. Explain the sour and the most important property in the amino finally, then it is easy very the ion turns of characteristic:On the sour numerator of the same of amino , bring to have the positive electricity and negative electricity meanwhile;When these amino is sour to constitute the protein, this kind of ion property also continues the protein, educating the ion characteristic of the protein, giving the protein should have of the form and activity.

Peptide

Many numerator head and tails with sour amino's link

The Peptide bond of born:

The amino is sour to be like the happy high toy or wooden blocks, can connect with a per head and tail, constituting a huge numerator protein.The copular method is very simple, ex- carboxylase with sour amino and the back a amino with sour amino , was responded by dehydration then.All still have a amino and thecarboxylase a peptide's(1-2), can continue to link bottom.The new key that thus two with sour amino produce, be called the peptide Key(the peptide bond), as above the C-N in the diagram. Many peptide ? C-N.The key constituted the framework of the protein, the protein is a biologic important numerator, therefore peptide Key also can be treated as basic framework that combines the life.

(Peptide)of the detection is seen as prevent an aging big breakthrough of the skin, guide the hairdressing protects the skin science and technology to exceed into the cell to protect the skin of new era, in 2002 skin science conference in the worlds, the argument Peptide is converse the skin of aging all-new biotechnology of a, 2003 the skin section annual convention up the experiment that announce the Peptide effect announces, the experiment result shows only the centesimal dosage of needing the equal to vitamin A to can immediately acquire the same skin improvement effect, and more more gentle than the vitamin A.

So-called Peptide is also a protein, protein by amino acids(the Amino Acid) constitute, and Peptide by more than 2-50 amino acidses constitute, have the physiology activity, what to play is the role of the hormone or enzyme.The Peptide that uses in the cosmetics, have another is connected and become by 3-7 amino acidses, often speak most currently of is 5 or 6 two kinds of, because the amino acids contain more than 20 kinds, as long as a the amino acids category that connects to constitute is different, there will be the different function.

The Peptide molecular weight is very small, don't need to carry the body particularly or emulsify the technique, but because the Peptide belongs to get close to water sex, combine fat, become the lipid solubility Peptide, wear more easily deeply the skin to reach the result.

Peptode Key Peptide Bond:

l The Peptide Bond though single key but have a pair of keys property.

l Six atoms of the perimeter of Peptide Bond are on same flat surface.

l In front and back two α -carbons with sour amino's are in the opposite angles(Trans).

How treat a Peptide common sense:

How treat a peptide:

Peptide by several amino's sour with peptide. [1]The key constitutes, there is N-C-C-N-C-C on its framework-of the repetition configures, the protein also is such.For such structure, have what time the that should notice and can recognize:

(1)The atom of the both ends distinguish why? Each belong to what organic functions regiment?

(2) Where is a carbon on the framework? Why to find out a carbon?

(3) Can point out each amino of unit sour?

(4) Can point out each peptide.Where is the key?

OHT Peptide-3 is a concentrated, non-oily formulation of the essential peptides, which absorbs quickly into the skin. These peptides are natural skin rejuvenating proteins formed inside our body naturally, acting as excellent emollients (soothing agents of the skin), as well as superb wrinkle-preventive components. The essential peptides formulation of the OHT Peptide-3 cream includes peptide proteins like Palmitoyl Pentapeptide-3, Palmitoyl Tetrapeptide-3, Palmitoyl Oligopeptide etc.

While the research behind the formulation of peptides in the OHT Peptide-3 cream was to find specific solutions to address the aging skin, the primary objective was to find a peptides formulation that would enhance the stimulation of fibroblasts in the skin to produce collagen and hyaluronic acid. While among the peptides formulation, the Palmitoyl Pentapeptide-3 has helped to stimulate collagen production and to thicken the epidermis layer of the skin, clinical reviews have shown that it also has a dramatic effect on reducing the quantity and depth of wrinkles, besides improving surface smoothness to a great extent. So, Palmitoyl Pentapeptide-3, the most essential anti-aging skin care agent among the peptides, consists of a stimulating natural biological process that reverses the aging process of the skin.

Another interesting peptides formulation in the OHT Peptide-3 cream is the Palmitoyl Tetrapeptide-3, (a synthetic peptide). While medical science says that inflammation is a protective response to injury or destruction of tissue, it results in high levels of inflammatory proteins and slower tissue regeneration as we age. The Palmitoyl Tetrapeptide-3 is the most important among the peptides to suppress the body's production of interleukins, since these are the chemical messengers that trigger the body's inflammatory response. Besides, the Biopeptide-CL (synthetic protein combined with palmitic acid) is the most significant among the peptides in the OHT peptide-3 cream, which acts as a man-made precursor to collagen production.

The polypeptide chain

Amino acids in proteins (or polypeptides) are joined together by peptide bonds.

The sequence of R-groups along the chain is called the primary structure. Secondary structure refers to the local folding of the polypeptide chain. Tertiary structure is the arrangement of secondary structure elements in 3 dimensions and quaternary structure describes the arrangement of a protein's subunits.

Linus Pauling and Robert Corey analysed the geometry and dimensions of the peptide bonds in the crystal structures of molecules containing one or a few peptide bonds. Their results are summarised in this diagram where the consensus bond lengths are shown in Angstrom units. Bond angles in degrees are also shown for the peptide N and C atoms.

Note that the C-N bond length of the peptide is 10% shorter than that found in usual C-N amine bonds. This is because the peptide bond has some double bond character (40%) due to resonance which occurs with amides. The two canonical structures are:

As a consequence of this resonance all peptide bonds in protein structures are found to be almost planar, ie atoms Calpha(i), C(i), O(i), N(i+1) H(i+1) and Calpha(i+1) are approximately co-planar. This rigidity of the peptide bond reduces the degrees of freedom of the polypeptide during folding.

The peptide bond nearly always has the trans configuration since it is more favourable than cis, which is sometimes found to occur with proline residues.


As can be seen above, steric hindrance between the functional groups attached to the Calpha atoms will be greater in the cis configuration. However for proline residues, the cyclic nature of the side chain means that both cis and trans configurations have more equivalent energies. Thus proline is found in the cis configuration more frequently than other amino acids. The omega torsion angle of proline will be close to zero degrees for the cis configuration, or most often, 180 degrees for the trans configuration.



(Peptide)of the detection is seen as prevent an aging big breakthrough of the skin, guide the hairdressing protects the skin science and technology to exceed into the cell to protect the skin of new era, in 2002 skin science conference in the worlds, the argument Peptide is converse the skin of aging all-new biotechnology of a, 2003 the skin section annual convention up the experiment that announce the Peptide effect announces, the experiment result shows only the centesimal dosage of needing the equal to vitamin A to can immediately acquire the same skin improvement effect, and more more gentle than the vitamin A.

So-called Peptide is also a protein, protein by amino acids(the Amino Acid) constitute, and Peptide by more than 2-50 amino acidses constitute, have the physiology activity, what to play is the role of the hormone or enzyme.The Peptide that uses in the cosmetics, have another is connected and become by 3-7 amino acidses, often speak most currently of is 5 or 6 two kinds of, because the amino acids contain more than 20 kinds, as long as a the amino acids category that connects to constitute is different, there will be the different function.

The Peptide molecular weight is very small, don't need to carry the body particularly or emulsify the technique, but because the Peptide belongs to get close to water sex, combine fat, become the lipid solubility Peptide, wear more easily deeply the skin to reach the result. After completing the combination of the sequence, will contain the tree ester(500 mgs) of the peptide to place to go into a bottom bottle, it contains the 10 ml aqua to include 2.5% B alkane two sulphur (ethanedithiol)s/1.25% benzene oxygen methane anisole/1.25% H2 Os/95% TFA carries on incising the reaction, responding also is dissolved in the 50 mls after indoor temperature carrying on 2nd after hours, filtering aqua and joining the cold B ether of the 200 mls to precipitate the peptide, thick peptide then in collecting, 5% acetic acid aqua, again to the refrigeration aridity.

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